METHOD FOR PERSONIFIED PHOTODYNAMIC THERAPY OF EXTENSIVE COSMETIC SKIN DEFECTS

摘要

FIELD: cosmetology.;SUBSTANCE: drug based on 5-aminolevulinic acid is applied on the entire face and / or head skin. After 1 hour after drug application on skin, fluorescence spectroscopy is carried out, determining the fluorescence intensity (FI), on the basis of which a dose of laser irradiation for PDT is chosen from the range of 5-45 J/cm². The lower the FI, the smaller the dose of irradiation. PDT irradiation of the entire skin is carried out using laser radiation with a wavelength of 400-800 nm.;EFFECT: method allows to increase the PDT efficiency of extensive cosmetic skin changes due to personified selection of the therapeutic dose of laser irradiation taking into account the quantitative measurement of accumulation level of 5-ALA of induced protoporphyrin IX by fluorescence spectroscopy method.;4 dwg, 2 ex