Synchronized variation of sources conditions of a mass spectrometer with chemical ionization at atmospheric pressure, which is coupled with a chromatograph, in order to improve stability during the analysis

摘要

It is a mass spectrometer is created, which comprises: a gas chromatography - separating device, a atmospheres pressure ionization - ion source and a control system, the adapted to and is adapted to: (i) operating the atmospheres pressure ionization - ion source in the case of one or several first settings for a first time span, during one or more solvent from the gas chromatography - separating device during a solution means front eluting; and then (ii) operating the atmospheres pressure ionization - ion source in one or more second different settings for a subsequent second time span, during one or more analytes from the gas chromatography - separating device eluting.