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1,1'-DIADAMANTYL CARBOXYLIC ACIDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE

机译：1,1'-二金刚烷酸，含有此类化合物的药物及其用途

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摘要

The present invention relates to compounds defined by formula (I) wherein the group R is defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases.

机译：本发明涉及由式（I）定义的化合物，其中基团R如权利要求1所定义，具有有价值的药理活性。特别地，该化合物是11-羟基类固醇脱氢酶（HSD）1的抑制剂，因此适用于治疗和预防可受该酶抑制影响的疾病，例如代谢疾病。

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公开/公告号EP2318355B1

专利类型
公开/公告日2018-09-12

原文格式PDF
申请/专利权人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH;
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申请/专利号EP20090781046
发明设计人 ECKHARDT MATTHIAS;HAMILTON BRADFORD S.;HIMMELSBACH FRANK;
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申请日2009-07-24
分类号C07C255/45;C07C69;C07D263/56;C07C271/24;C07D217/04;C07C69/753;C07D223/16;C07D235/16;C07C211/35;C07D239/74;C07D241/04;C07C233/32;C07D257/04;C07D205/04;C07D207/08;C07D271/06;C07D209/08;C07D211/56;C07D295/185;C07D213/64;C07C62/06;
国家 EP
入库时间 2022-08-21 13:20:23

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