Novel hexon isolated from simian adenovirus serotype 19 encoded in the polynucleotide defined as SEQ ID NO: 3, hepervariable region thereof, chimeric adenovirus comprising the same, and therapeutic use thereof provides a solution to the problem of safety and effective systemic treatment for developing gene therapeutic agents using adenovirus.
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机译:从编码于SEQ ID NO:3的多核苷酸中编码的猿猴腺病毒血清型19分离的新型六邻体,其高变区,包含其的嵌合腺病毒及其治疗用途为解决开发基因治疗药的安全性和有效全身性问题提供了解决方案代理使用腺病毒。
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