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AMINO ACID, ORGANIC ACID, AND SUGAR ANALYSIS PRETREATMENT DEVICE AND ANALYSIS PRETREATMENT METHOD

机译:氨基酸,有机酸和糖的分析预处理装置及分析预处理方法

摘要

A pre-analysis treatment device usable for an amino acid, organic acid, and glucide includes an ion-exchange unit configured to load a test sample on a solid-phase cartridge S having a strong ion-exchange resin phase, to allow the strong ion-exchange resin phase to adsorb a predetermined organic compound, then supply a dehydration solvent to dehydrate the strong ion-exchange resin phase, and a derivatization unit configured to feed a predetermined amount of the derivatization reagent to the dehydrated strong ion-exchange resin phase to allow the derivatization reagent to retain for a predetermined time period, thereby trimethylsilylating the organic compound adsorbed on the strong ion-exchange resin phase, and simultaneously desorbing the trimethylsilylated organic compound from the strong ion-exchange resin phase, and then supply a push-out solvent to push the trimethylsilylated organic compound desorbed, out of the solid-phase cartridge S. The device enables at least one organic compound selected from amino acids, organic acids and glucides contained in a test sample to be derivatized and collected easily in a short period of time, and automation of the pre-analysis treatment.
机译:可用于氨基酸,有机酸和葡糖的分析前处理装置包括离子交换单元,该离子交换单元构造成将测试样品装载在具有强离子交换树脂相的固相小柱S上,以允许强离子交换树脂相以吸附预定的有机化合物,然后提供脱水溶剂以使强离子交换树脂相脱水,并且衍生单元配置为将预定量的衍生化试剂进料到脱水的强离子交换树脂相中。使衍生化试剂保留预定的时间,从而使吸附在强离子交换树脂相上的有机化合物发生三甲基甲硅烷基化,同时使三甲基甲硅烷基化的有机化合物从强离子交换树脂相中解吸,然后提供出料溶剂以将解吸的三甲基甲硅烷基化的有机化合物推出固相色谱柱S。该设备可实现至少一种有机化合物该化合物选自测试样品中包含的氨基酸,有机酸和葡萄糖,可在短时间内轻松衍生和收集,并实现了分析前处理的自动化。

著录项

  • 公开/公告号EP3182117A4

    专利类型

  • 公开/公告日2018-04-25

    原文格式PDF

  • 申请/专利权人 AISTI SCIENCE CO. LTD.;

    申请/专利号EP20150832173

  • 发明设计人 SASANO RYOICHI;

    申请日2015-08-10

  • 分类号G01N1/40;G01N30/96;G01N30/06;G01N30/88;

  • 国家 EP

  • 入库时间 2022-08-21 13:18:54

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