MICROFLUIDIC-NANOFLUIDIC DEVICES FOR DETECTION AND MEASUREMENT OF REDOX ACTIVE SUBSTANCES

摘要

Devices including an electrode assembly within a nanofluidic channel are provided for electrochemical measurement of the concentration of a redox active substance. Also provided are methods of fabricating the devices and methods of measuring a concentration of a redox active substance using the devices. The devices and methods, and sensors embodying them, provide fast and sensitive detection of the presence of a microorganism by detecting a redox active substance produced by the microorganism while preventing venting access of the microoganism itself to the electrode assembly.