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METHODS AND DEVICES RELATING TO THE DETECTION OF ORAL CANCER BIOMARKERS

机译:与口腔癌生物标志物检测有关的方法和设备

摘要

Disclosed is an ex vivo method for detecting plural predefined oral biomarkers within biological material present in a human oral cavity when oral cancerous activity is present in said cavity, the method comprising the steps of: i) providing a solid support for accepting a sample of biological material from the oral cavity; ii) transferring a sample of the biological material to the solid support, iii) performing one or more ex vivo plural assays to detect the presence of said plural biomarkers on the solid support, in the form of one or more nucleic acid sequences, and/or one or more proteins, and/or one or more enzymes indicative of said oral cancerous activity. A sample swab 10 suitable for use with the above methods is disclosed also.
机译:公开了一种当所述口腔中存在口腔癌活性时用于检测人口腔中存在的生物材料中的多种预定的口腔生物标志物的离体方法,该方法包括以下步骤:i)提供用于接受生物样品的固体支持物。来自口腔的物质; ii)将生物材料的样品转移到固相支持物上,iii)进行一种或多种离体化验以检测固相支持物上以一种或多种核酸序列形式存在的所述多种生物标志物,和/或一种或多种蛋白质和/或一种或多种指示所述口腔癌活性的酶。还公开了适用于上述方法的样品拭子10。

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