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A POLYMER MICROPARTICLE-BASED METHOD FOR PROBE DEPOSITION IN LABEL-FREE BIOSENSORS
A POLYMER MICROPARTICLE-BASED METHOD FOR PROBE DEPOSITION IN LABEL-FREE BIOSENSORS
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机译:无标签生物传感器中基于聚合物微粒的探针沉积方法
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摘要
Disclosed is a sensor chip for detecting a target molecule in a sample. The sensor chip includes a substrate having a surface and a layer of hydrogel particles immobilized on the substrate surface at two or more locations on the surface, wherein the hydrogel particles at a first location comprise a plurality of first probe molecules bound to the particles and the hydrogel particles at a second location comprise a plurality of second probe molecules bound to the particles. Systems that include the sensor chip, as well as methods of preparing and using the sensor chip, are also disclosed.
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