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COMPOUNDS AND METHODS FOR TREATING, DETECTING, AND IDENTIFYING COMPOUNDS TO TREAT APICOMPLEXAN PARASITIC DISEASES

机译：用于治疗，检测和鉴定可治愈API复杂性寄生虫病的化合物和方法

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摘要

Disclosed herein; are novel compounds for treating apicomplexan parasite related disorders, methods for their use; cell line and non-human animal models of the dormant parasite phenotype and methods for their use in identifying new drugs to treat apicomplexan parasite related disorders, and biomarkers to identify disease due to the parasite and its response to treatment.

机译：在此披露;是用于治疗apicomplexan寄生虫相关疾病的新型化合物，其使用方法;休眠寄生虫表型的细胞系和非人类动物模型，以及它们在鉴定新的药物以治疗apicomplexan寄生虫相关疾病方面的方法，以及用于鉴定由寄生虫引起的疾病及其对治疗反应的生物标记物的方法。

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公开/公告号EP3394032A1

专利类型
公开/公告日2018-10-31

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申请/专利权人 THE UNIVERSITY OF CHICAGO;INSTITUTE FOR SYSTEMS BIOLOGY;UNIVERSITY OF LEEDS;THE J. CRAIG VENTER INSTITUTE;THE UNIVERSITY OF STRATHCLYDE;U.S. GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY MEDICAL COMMAND (MEDCOM);
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申请/专利号EP20160879977
发明设计人 MCLEOD RIMA;MCPHILLIE MARTIN;FISHWICK COLIN W.G.;LORENZI HERNAN ALEJANDRO;WANG KAI;KIM TEAK-KYUN;ZHOU YONG;HOOD LEROY E.;ZHOU YING;EL BISSATI KAMAL;GORDON JAMES;HICKMAN MARK;LI QIGUI;ROBERTS CRAIG;
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申请日2016-12-20
分类号C07D215/233;C07D401/04;C07D401/10;C07D487/04;C07D239/96;A61K31/47;A61K31/4709;A61K31/517;A61K31/519;A61P33/02;
国家 EP
入库时间 2022-08-21 13:16:34

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