SYSTEM AND METHOD FOR MODELLING OF DOSE CALCULATION IN RADIOTHERAPY TREATMENT PLANNING

摘要

A method is proposed for evaluating the robustness of a radiotherapy treatment plan. The method comprises, defining a number of scenarios, each comprising one or more errors for each fraction of the plan, including interfractional and/or intrafractional errors, and calculating a dose distribution resulting from the scenario;The robustness of the plan is then evaluated based at least one of the followingi. the probability of fulfilling a set of clinical goals estimated as the clinical goal fulfilment over the scenariosii. the range of DVH values over the scenariosiii. dose statistics for dose distributions defined as voxel-wise aggregates over the scenario doses