METHOD AND DEVICE FOR THE NON-INVASIVE INDIRECT IDENTIFICATION OF SITES OF ALTERATIONS OF THE BLOOD-RETINAL BARRIER

摘要

Method and device for detecting sites of low optical reflectivity from optical coherence tomography, OCT, of the retina comprising segmenting retinal layers from OCT data; calculating the optical reflectivity of each of the segmented retinal layers from the OCT data; detecting sites of low optical reflectivity from the calculated optical reflectivity of the segmented retinal layers. The calculated optical reflectivity may be compared against a predetermined threshold obtained from a healthy population. Segmenting may be carried out according to the optical reflectivity of each identified retinal layer. OCT-Microangiography data may be displayed side-by-side or superimposed with the enface images of the calculated optical reflectivity. The disclosure is namely useful for identifying abnormal increases of intercellular fluid or extracellular space in the retina, for non-invasive identification of sites of alterations of the blood-retinal barrier. The device may be combined with OCT equipment, in particular for displaying the detected sites of low optical reflectivity.