PROBLEM TO BE SOLVED: To provide a reflux esophagitis preventive agent that can be used safely for not only a patient who has contracted reflux esophagitis, but also a healthy subject who needs preventive measures against the disease.SOLUTION: A reflux esophagitis preventive agent contains collagen as an active ingredient. The collagen is preferably collagen from fish skin, particularly from Thunnus thynnus.SELECTED DRAWING: None
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