首页> 外国专利> NOVEL D3 DOPAMINE RECEPTOR AGONISTS TO TREAT DYSKINESIA IN PARKINSON'S DISEASE

NOVEL D3 DOPAMINE RECEPTOR AGONISTS TO TREAT DYSKINESIA IN PARKINSON'S DISEASE

机译:新型D3多巴胺受体激动剂治疗帕金森氏病的运动障碍

摘要

PROBLEM TO BE SOLVED: To provide a method for inhibiting, suppressing, or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's disease.SOLUTION: According to the present invention, there is provided a pharmaceutical composition comprising at least one compound selected from an indolylalkylamine derivative represented by the formula (I) and a benzimidazolylalkylamine derivative. (Rto Rare H, cyano, hydroxyl, amino, acetamide, etc; Rand Rare H, Calkyl, substitutedalkyl, heteroalkyl, heterocyclyl, substituted heterocyclyl, etc.; and n is an integer of 2 to 5)SELECTED DRAWING: None
机译:解决的问题:提供一种抑制,抑制或预防帕金森氏病患者左旋多巴诱发的运动障碍的方法。解决方案:根据本发明,提供了一种药物组合物,其包含至少一种选自以下的化合物:由式(I)表示的吲哚基烷基胺衍生物和苯并咪唑基烷基胺衍生物。 (Rto稀有H,氰基,羟基,氨基,乙酰胺等; Rand稀有H,C1烷基,取代的烷基,杂烷基,杂环基,取代的杂环基等;且n为2至5的整数)

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