Devices, systems and methods for enhancing intraluminal drug delivery and uptake

摘要

The present disclosure relates generally to methods, devices and systems related to applying a drug or therapeutic agent to a biological conduit, such as a vascular lumen. More specifically, the present invention enhances the uptake of drugs or therapeutic agents encapsulated in microbubbles in combination with ultrasound energy and pulse generation that can be matched in frequency to the patient's blood pulse. Applying a drug or therapeutic agent periodically using a device.