Use of C-type natriuretic peptide variants for the treatment of skeletal dysplasia

摘要

The present disclosure treats one or more skeletal dysplasia symptoms such as skeletal dysplasia, long bone growth or growth rate, and other disorders having skeletal dysplasia and / or CNP-related symptoms or components. Of C-type natriuretic peptide (CNP), and the use of novel pharmaceutical compositions and formulations comprising CNP variant peptides are provided. The variant treats skeletal dysplasia, treats one or more skeletal dysplasia-related symptoms, or one or more effects of skeletal dysplasia in a subject suffering from skeletal dysplasia, or Physiological symptoms can be improved.