Ionizing radiation sterilization of bacteria-derived minicell biopharmaceuticals and methods of use

摘要

Disclosed herein are methods for completely sterilizing bacterially derived minicells or compositions comprising bacterially derived minicells by ionizing radiation. Also disclosed are completely sterilized bacteria-derived minicells, pharmaceutical compositions comprising said bacteria-derived minicells, and methods of using said bacteria-derived minicells and pharmaceutical compositions.