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3-Carbamoylphenyl-4-carboxamide and isophthalamide derivatives as inhibitors of WNT signaling pathway

机译:3-氨基甲酰基苯基-4-羧酰胺和间苯二甲酰胺衍生物作为WNT信号通路的抑制剂

摘要

The present invention relates to inhibitors of the Wnt signaling pathway of general formula (I) as described and defined herein, methods for preparing said compounds, intermediate compounds useful for preparing said compounds, said compounds Pharmaceutical compositions and combinations comprising, as well as the use of said compounds for the manufacture of pharmaceutical compositions for treating or preventing diseases, in particular hyperproliferative disorders, as sole agents or in combination with other active ingredients.
机译:本发明涉及如本文所述和定义的通式(I)的Wnt信号传导途径的抑制剂,制备所述化合物的方法,可用于制备所述化合物的中间体化合物,所述化合物,药物组合物和组合物,以及其用途所述化合物的制备,所述化合物用于制造治疗或预防疾病,特别是过度增殖性疾病的药物组合物,其为单独的药剂或与其他活性成分组合。

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