首页> 外国专利> ALCOHOL METABOLISM PROMOTING AGENT AND ALCOHOL DISORDER PREVENTION FOOD AND DRINK

ALCOHOL METABOLISM PROMOTING AGENT AND ALCOHOL DISORDER PREVENTION FOOD AND DRINK

机译:酒精代谢促进剂和酒精紊乱预防食品和饮料

摘要

PROBLEM TO BE SOLVED: To provide agents and food and drinks which activate a TCA cycle whose function is inhibited by in vivo alcohol metabolism, and β oxidation, and which promote regeneration of NADthrough the activation of oxidative phosphorylation and are simultaneously effective in protecting cells from oxidative stress causing hepatopathy or in repairing cells damaged by the stress.SOLUTION: The alcohol metabolism promoting agent of the present invention comprises an energy metabolism promoting agent in which AMP is used as an indirect ATP synthetic substrate. As for the energy metabolism promoting agent, preferably citric acid, vitamin B1, and the like are comprised. Preferably, the alcohol metabolism promoting agent comprises an Nrf2 activator. The Nrf2 activator comprises a food factor comprising lipoic acid, curcumin, sesamin, and the like, or an extract obtained from Tuber melanosporum and the like. Preferably, an alcohol disorder prevention food and drink containing the agent and having the form of a jelly like food or a tablet is provided.SELECTED DRAWING: Figure 1
机译:解决的问题:提供能激活TCA循环的试剂,食品和饮料,其功能受到体内酒精代谢和β氧化的抑制,并通过激活氧化磷酸化促进NAD的再生,同时有效保护细胞免受氧化应激引起的肝病或修复受应激破坏的细胞。解决方案:本发明的醇代谢促进剂包括能量代谢促进剂,其中AMP被用作间接ATP合成底物。作为能量代谢促进剂,优选包含柠檬酸,维生素B1等。优选地,醇代谢促进剂包含Nrf2活化剂。 Nrf 2活化剂包括包含硫辛酸,姜黄素,芝麻素等的食物因子,或得自黑薯块茎等的提取物。优选地,提供包含该试剂并且呈果冻状的食品或片剂形式的预防酒精紊乱的食品和饮料。图1:

著录项

  • 公开/公告号JP2018020963A

    专利类型

  • 公开/公告日2018-02-08

    原文格式PDF

  • 申请/专利权人 NIIGATA BEER CO LTD;

    申请/专利号JP20160151049

  • 发明设计人 USAMI TAKESHI;KONISHI TETSUYA;

    申请日2016-08-01

  • 分类号A61K31/7076;A61K31/194;A61K31/51;A61K31/525;A61K31/455;A61K31/4415;A61K31/197;A61P3;A61P39/02;A61K31/381;A61K31/121;A61K31/05;A23L33/10;A23L33/15;A23L33/105;A61K36/9068;A61K36/19;A61K36/9066;A61K36/28;A61K36/235;A61K36/79;A61K36/254;A61K36/605;A61K36/062;

  • 国家 JP

  • 入库时间 2022-08-21 13:11:03

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