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Methods, tools and systems for evaluation, prevention, management and treatment selection for type 2 diabetes

机译:评估,预防,管理和选择2型糖尿病的方法,工具和系统

摘要

The present invention provides a method for assessing susceptibility to type 2 diabetes and / or predicting treatment responsiveness in a human subject, comprising: SLC16A11-rs75493593; HNF1A-rs483353044; TCF7L2-rs7903146; CDKN2A / B-rs10811661; -Rs7756992; SLC30A8-rs3802177; IGF2BP2-rs4402960; FTO-rs9936385; PPARG-rs1801282; HHEX / IDE-rs1111875; ADCY5-rs11717195; rs5219 or A single nucleotide polymorphism (SNP) selected from the group consisting of: and / or Including determining identity. A genotyping tool and a type 2 diabetes risk assessment system for use in the methods of the present invention are also provided. [Selection] Figure 4
机译:本发明提供了一种评估人类受试者对2型糖尿病的易感性和/或预测治疗反应性的方法,该方法包括:SLC16A11-rs75493593;和HNF1A-rs483353044; TCF7L2-rs7903146; CDKN2A / B-rs10811661; -Rs7756992; SLC30A8-rs3802177; IGF2BP2-rs4402960; FTO-rs9936385; PPARG-rs1801282; HHEX / IDE-rs1111875; ADCY5-rs11717195; rs5219或单核苷酸多态性(SNP),选自:和/或包括确定同一性。还提供了用于本发明方法的基因分型工具和2型糖尿病风险评估系统。 [选择]图4

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