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Composition for inhibiting ADAMTS-5 or ADAM17 expression and method thereof
Composition for inhibiting ADAMTS-5 or ADAM17 expression and method thereof
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机译:抑制ADAMTS-5或ADAM17表达的组合物及其方法
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摘要
The present invention discloses siRNAs or chemically modified siRNAs targeting ADAMTS-5 or ADAM17 that suppress the expression of ADAMTS-5 or ADAM17. Further disclosed are applications of siRNAs in the treatment of diseases related to ADAMTS-5 or ADAM17, such as treating arthritis and other inflammation-related diseases by injecting siRNAs or formulations thereof into the joint cavity of a patient. [Selection figure] None
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