Complex microbial preparations for long-term control or prevention of opportunistic microbial infections

摘要

The complex microbial formulation contains the components of the microscopic oomycete Psium origolandrum and the physiological microflora. The microscopic oomycete Psium origandrum and physiological microflora components are present in the composite formulation in a form that promotes their germination, subsequent growth from target tissues and colony formation. The microscopic oomycete pisium oliganlam is included in an amount of 103-107 CFU (colony forming units), preferably 104-105 CFU, per application cycle. The physiological microflora component comprises 5 × 10 5 to 5 × 10 10 CFU, preferably 5 × 10 7 to 5 × 10 9 per application cycle. The fermentation substrate found in Oomyces pisium origolandrum is a nutrient source for both microbial components. The complex microbial formulation contains at least one auxiliary substance from the group comprising desiccants, buffer system components, anti-caking substances and agents for creating a physiological osmotic environment. The physiological microbiota component is one of the components of the human microflora, one of the microorganisms of the green complex, such as the bacterium Capnositophaga sputigena, or one of the components of the healthy skin microflora, such as the bacterium Staphylococcus epidermidis, Or one of the components of a healthy vaginal microflora, such as peroxide-producing Lactobacillus crispatas. Either the microscopic oomycete pysium oliligand or the physiological microbiota component is present in the complex microbial formulation in the form of inactivated cells, cell extracts or isolated cell fractions. The microbial activator of Oomyces pycium origolandrum is yeast autolysate in an amount of 0.1 to 10% by weight of the total amount of the complex microbial preparation. Supplementary substances are adjusted so that they can be applied in the form of ointments, creams, oils or suppositories, or in the form of a liquid aqueous formulation.