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Disease onset determination device, disease onset determination method, disease feature extraction device, and disease feature extraction method

机译:疾病发作确定装置,疾病发作确定方法,疾病特征提取装置和疾病特征提取方法

摘要

It is possible to determine the morbidity of a disease by learning with a neural network using data on the expression level of a biomarker, and to extract a biomarker characteristic of the disease using a neural network. A sample model in which the expression level of each of a plurality of types of biomarkers is recorded for each individual is acquired and machine learning is performed using training data to generate a learned model that can determine the prevalence of a disease obtained in advance. Then, for this learned model, a plurality of sample data with label information affected by a disease are input and calculated, and a plurality of biologics obtained by the learned model by calculating the morbidity for each sample data. The importance level of each marker feature is digitized, and a predetermined number of biomarkers are extracted as characteristic biomarkers related to the disease based on the digitized importance level of all sample data for each biomarker. [Selection] Figure 2
机译:通过使用有关生物标志物表达水平的数据的神经网络学习来确定疾病的发病率,并使用神经网络提取疾病的生物标志物特征是可能的。获取样本模型,其中针对每个个体记录了多种类型的生物标志物的每种的表达水平,并且使用训练数据执行机器学习以生成可以确定预先获得的疾病的流行程度的学习模型。然后,对于该学习模型,输入并计算具有受疾病影响的标签信息的多个样本数据,并且通过计算每个样本数据的发病率,通过该学习模型获得多个生物制剂。数字化每个标记特征的重要性级别,并基于每个生物标记的所有样本数据的数字化重要性级别,提取预定数量的生物标记作为与疾病相关的特征性生物标记。 [选择]图2

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