2- (4- (2- (1-Isopropyl-3-methyl-1H-1,2,4-triazol-5-yl) -5,6-dihydrobenzo f imidazo 1,2-d 1,4 Oxazepin-9-yl) -1H-pyrazol-1-yl) -2-methylpropanamide polymorphs, methods for their production and pharmaceutical use

摘要

The present invention relates to crystalline polymorphs of (2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide (GDC-0032, taselisib), methods of use, and processes of preparing thereof.