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Ion-exchange chromatography with improved selectivity for separating polypeptide monomers, aggregates and fragments by adjusting the mobile phase
Ion-exchange chromatography with improved selectivity for separating polypeptide monomers, aggregates and fragments by adjusting the mobile phase
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机译:离子交换色谱具有更高的选择性,可通过调节流动相来分离多肽单体,聚集体和片段
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摘要
Herein is reported a method for producing a polypeptide in monomeric form comprising the following step: recovering the polypeptide in monomeric form from an ion exchange chromatography material by applying a solution comprising a nonionic polymer and an additive.
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