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Systems and methods for tuning closed-loop phasic burst stimulation based on a phase response curve
Systems and methods for tuning closed-loop phasic burst stimulation based on a phase response curve
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机译:基于相位响应曲线调整闭环相位猝发刺激的系统和方法
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摘要
Systems and methods are provided for determining optimized settings for a closed-loop stimulation system based on analyzing a phase response curve measured from electrophysiological activity, such as electrical nerve activity or electrical muscle activity. The slope of the phase response curve is computed and used to determine a phase window during which phasic burst stimulation should be provided to achieve a desired effect on oscillations in the subject. When the slope of the phase response curve is positive, a phasic burst stimulation applied during the phase window will decrease synchrony of the oscillations. When the slope of the phase response curve is negative, a phasic burst stimulation applied during the phase window will increase synchrony of the oscillations.
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