The present invention also relates to pharmaceutical compositions useful for treating or preventing a disorder responsive to the blockade of sodium ion channels, especially Nav1.7 sodium ion channels. The present invention further provides methods of treating a disorder responsive to the blockade of sodium channels, and particularly Nav1.7 sodium channels, in a mammal suffering from excess activity of said channels, compositions and methods for providing analgesia by administering a peptide of the invention.
展开▼
机译:本发明还涉及可用于治疗或预防对钠离子通道,特别是Na v Sub> 1.7钠离子通道的阻断有响应的疾病的药物组合物。本发明进一步提供了在患有所述通道过度活性的哺乳动物中治疗对钠通道,特别是Na v Sub> 1.7钠通道的阻断有反应的疾病的方法,组合物和提供镇痛的方法通过施用本发明的肽。
展开▼