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Devices and methods for local delivery of drug to upper urinary tract
Devices and methods for local delivery of drug to upper urinary tract
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机译:用于将药物局部递送至上尿路的装置和方法
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摘要
Drug delivery devices include a flexible elongate body having a bladder end portion, a kidney end portion, and a drug lumen extending therebetween; and a drug reservoir which is located at the bladder end portion, contains a drug, and is defined at least in part by a semi-permeable wall. Methods include inserting the device into the ureter of a patient and permitting water in the bladder to diffuse through the semi-permeable wall to create an osmotic pressure to pump the drug through the drug lumen and out of the device at the kidney end portion and into the renal pelvis.
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