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Biomarkers for Diagnosis and Prognosis of Lung Cancer
Biomarkers for Diagnosis and Prognosis of Lung Cancer
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机译:肺癌诊断和预后的生物标志物
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摘要
Provided herein are methods for non-invasively diagnosing and/or prognosing a lung cancer and for determining the efficacy of a therapeutic treatment regimen for the lung cancer. Expression levels of at least two small non-coding RNAs, for example, microRNAs and small nucleolar RNAs, are measured and used to calculate an area under the curve (AUC) that provides a probability of lung cancer in the subject. The smoking history of the subject and, if present, the size of pulmonary nodules may be incorporated into the calculation.
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