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METHODS OF SELECTING AND ISOLATING CANCER STEM CELLS
METHODS OF SELECTING AND ISOLATING CANCER STEM CELLS
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机译:肿瘤干细胞的选择和分离方法
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摘要
Provided herein are methods for selecting/identifying and/or isolating cancer stem cells from a biological sample or a cell culture sample using a fluorescent glucose analog. Also provided herein are methods for selecting/identifying and/or isolating leukemia stem cells and subpopulations thereof. The present invention is based, in part, on the discovery that cancer stem cells can be selected/identified based upon a lower level of fluorescence of the fluorescent glucose analog compared to non-cancer stem cells and that specific genes are differentially expressed in leukemia stem cells compared to non-leukemia stem cells.
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