embedded image ;or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are as defined herein."/> SUBSTITUTED PYRIMIDINES FOR TREATMENT OF ACUTE COUGH, CHRONIC COUGH AND URGE TO COUGH
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SUBSTITUTED PYRIMIDINES FOR TREATMENT OF ACUTE COUGH, CHRONIC COUGH AND URGE TO COUGH

机译:取代的嘧啶类药物,用于治疗急性凝结,慢性凝结和急促凝结

摘要

Methods for treating cough, chronic cough and urges to cough associated with respiratory diseases with a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of Formula (I):; embedded image ;or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are as defined herein.
机译:用P2X3和/或P2X2 / 3受体拮抗剂治疗与呼吸系统疾病相关的咳嗽,慢性咳嗽和急咳的方法,该方法包括向有需要的受试者施用有效量的式(I)的化合物: ; “嵌入式图像” ;或其药学上可接受的盐,其中R 1 和R 2 如本文所定义。

著录项

  • 公开/公告号US2017326142A1

    专利类型

  • 公开/公告日2017-11-16

    原文格式PDF

  • 申请/专利权人 AFFERENT PHARMACEUTICALS. INC.;

    申请/专利号US201715665595

  • 发明设计人 ANTHONY P. FORD;BRUCE G. MCCARTHY;

    申请日2017-08-01

  • 分类号A61K31/505;A61K9/20;A61K9/20;A61K9;A61K9/20;A61K9/20;C07D239/48;A61K9/20;

  • 国家 US

  • 入库时间 2022-08-21 13:03:40

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