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INTRANASAL THERAPEUTIC DELIVERY OF ADENO-ASSOCIATED VIRUS TO CENTRAL NERVOUS SYSTEM
INTRANASAL THERAPEUTIC DELIVERY OF ADENO-ASSOCIATED VIRUS TO CENTRAL NERVOUS SYSTEM
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机译:鼻腔治疗性将伴有病毒的病毒转运至中枢神经系统
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摘要
A method to prevent, inhibit or treat one or more symptoms associated with disease of the central nervous system by intranasally, intrathecally, intracerebrovascularly or intravenously administering a rAAV encoding a gene product associated with the disease, e.g., a mammal in which the gene product is absent or present at a reduced level relative to a mammal without the disease, in an amount effective, e.g., to provide for cross-correction.
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