首页> 外国专利> A Composition Containing Protective Agent for Singlet Oxygen and A Preparation Method therefor

A Composition Containing Protective Agent for Singlet Oxygen and A Preparation Method therefor

机译:包含单线态氧保护剂的组合物及其制备方法

摘要

The Invention relates to a method to utilize the characteristic of a protective agent to incubate singlet oxygen and prolong its lifetime so as to provide abundant singlet oxygen with persistence and thus improve the effect of photodynamic therapy. The composition is composed of a functional substance that can prolong the lifetime of singlet oxygen, an emulsifier and a photosensitizer; the functional substance is emulsified into an emulsion through the emulsifier and delivered into a tumor tissue with the photosensitizer; then the photodynamic therapy can be conducted with the abundant singlet oxygen incubated by the functional substance that can prolong the lifetime of singlet oxygen and thus the effect of photodynamic therapy is improved.
机译:本发明涉及一种利用保护剂的特性来培育单线态氧并延长其寿命从而持久地提供丰富的单线态氧并由此改善光动力疗法效果的方法。该组合物由可以延长单线态氧的寿命的功能性物质,乳化剂和光敏剂组成。通过乳化剂将功能性物质乳化成乳状液,并与光敏剂一起传递到肿瘤组织中。然后可以在功能性物质的温育下用丰富的单线态氧进行光动力疗法,这样可以延长单线态氧的寿命,从而提高了光动力疗法的效果。

著录项

  • 公开/公告号US2018015164A1

    专利类型

  • 公开/公告日2018-01-18

    原文格式PDF

  • 申请/专利权人 NANJING UNIVERSITY;

    申请/专利号US201615547521

  • 申请日2016-12-29

  • 分类号A61K41;A61K47/44;A61K47/42;A61K47/18;A61K9/107;A61K47/06;A61K9/16;A61K9/127;B01J13/08;A61K47/34;

  • 国家 US

  • 入库时间 2022-08-21 13:03:37

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