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PER-WELL ILLUMINATION AND OPTICAL STIMULATION ARRANGEMENTS FOR ADVANCED MICROPLATE, MICROARRAY, AND MICROTITER TECHNOLOGIES
PER-WELL ILLUMINATION AND OPTICAL STIMULATION ARRANGEMENTS FOR ADVANCED MICROPLATE, MICROARRAY, AND MICROTITER TECHNOLOGIES
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机译:先进的微板,微阵列和微量滴定技术的每孔照明和光学刺激安排
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摘要
Arrangements for per-well illumination and optical stimulation arrangements for microplate, microtiter, and microarray technologies are presented. In example implementations, each individual well within in a conventional or specialized microplate can be fully or partially isolated with capping or other arrangements which can include conduits for controlled introduction, removal, and/or exchange of fluids and/or gases. Conduit networks can include small controllable valves that operate under software control, and micro-scale pumps can also be included. Conduit interconnections can include one or more of controllable-valve distribution buses, next-neighbor interconnections, and other active or passive interconnection topologies. Cap arrangements can include or provide one or more sensors of various types, including but not limited to selective gas sensors, chemical sensors, temperature sensors, pH sensors, biosensors, immunosensors, molecular-imprint sensors, optical sensors, fluorescence sensors, bioFETS, etc. Incubator interfacing and imaging are also described. The invention can be used for living cell culture or other applications.
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