首页> 外国专利> IMMUNOCHROMATOGRAPHIC TEST STRIP FOR DETECTING OBJECT IN RED BLOOD CELL-CONTAINING SAMPLE AND IMMUNOCHROMATOGRAPHY USING THE TEST STRIP

IMMUNOCHROMATOGRAPHIC TEST STRIP FOR DETECTING OBJECT IN RED BLOOD CELL-CONTAINING SAMPLE AND IMMUNOCHROMATOGRAPHY USING THE TEST STRIP

机译:免疫层析测试条,用于检测含红色血液细胞的样品中的对象,并使用该测试条进行免疫层析

摘要

A problem of the present invention is to provide an immunochromatographic test strip avoiding agglutination of colloidal gold while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a hemagglutinating agent and the colloidal gold conjugates as a detection reagent, and to provide immunochromatography using the test strip. To solve the problem, the present inventors reviewed the composition of the existing reagent itself from a completely different viewpoint rather than the selection of type or amount of polyanions, and as a result of extensive study on each element, the inventors surprisingly found that agglutination of colloidal gold may be suppressed by using a particular additive without neutralization by polyanions.
机译:本发明的一个问题是提供一种免疫层析测试条,其避免了胶态金的凝集,而在使用聚丙烯作为血凝剂和胶态金结合物作为检测的情况下,全血中的红细胞被凝集然后分离并去除了试剂,并使用试纸条进行免疫层析。为了解决该问题,本发明人从完全不同的观点而不是选择聚阴离子的类型或量的角度审查了现有试剂本身的组成,并且作为对每种元素的广泛研究的结果,本发明人令人惊讶地发现凝集的胶体金可以通过使用特定的添加剂而没有被聚阴离子中和来抑制。

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