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BIOMARKER FOR DIAGNOSIS OF DRUG ADDICTION AND KIT FOR DIAGNOSIS OF DRUG ADDICTION

机译:诊断药物成瘾的生物标志物和诊断药物成瘾的工具包

摘要

The present disclosure relates to a biomarker for diagnosis of drug addiction and a kit for diagnosis of drug addiction. The biomarker for diagnosis of drug addiction and the kit for diagnosis of drug addiction according to the present disclosure can determine drug addiction by using a molecular biological method. Especially, the present disclosure has investigated molecular biologically how microRNA functions in the human brain due to drug addiction and how the microRNA is transferred to blood or serum by using an exosome as a means of transport. Therefore, the problem that, even though the change in the expression pattern of the microRNA in the brain is validated, it is difficult to apply the change in the expression pattern in the brain for clinical purposes directly and simply, was solved.
机译:本公开涉及用于诊断药物成瘾的生物标记物和用于诊断药物成瘾的试剂盒。根据本公开的用于诊断药物成瘾的生物标志物和用于诊断药物成瘾的试剂盒可以通过使用分子生物学方法来确定药物成瘾。特别地,本公开已经在分子生物学上研究了微小RNA如何由于药物成瘾而在人脑中起作用以及如何通过使用外来体作为转运手段将微小RNA转移到血液或血清中。因此,解决了即使确认了大脑中的微小RNA的表达模式的变化,也难以直接且简单地将脑中的表达模式的变化直接应用于临床目的的问题。

著录项

  • 公开/公告号US2018305754A1

    专利类型

  • 公开/公告日2018-10-25

    原文格式PDF

  • 申请/专利权人 KOREA INSTITURE OF SCIENCE AND TECHNOLOGY;

    申请/专利号US201615743836

  • 发明设计人 HEH-IN IM;

    申请日2016-07-12

  • 分类号C12Q1/6876;G01N33/68;

  • 国家 US

  • 入库时间 2022-08-21 13:00:21

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