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System and method for irradiation therapy using voxel based functional measurements of organs at risk
System and method for irradiation therapy using voxel based functional measurements of organs at risk
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机译:使用基于体素的功能测量危险器官的放射疗法的系统和方法
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摘要
A method and apparatus for irradiation therapy using voxel based function measurements of organs-at-risk (OAR). The method includes determining size and location of each voxel of a plurality of voxels in a reference frame of a radiation device. The method further includes obtaining measurements that relate to utility of tissue type at each voxel. The method further includes determining a subset of the voxels that enclose an organ-at-risk (OAR) volume. The method further includes determining a value of a utility measure ƒj at each voxel of the subset based on a corresponding value of the measurements. The method further includes determining a series of beam shapes and intensities which minimize a value of an objective function that is based on a computed dose delivered to an OAR voxel multiplied by the utility measure ƒj for that voxel summed over all voxels.
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