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SYSTEM AND METHOD FOR EVALUATING EFFECTS OF ANTIARRHYTHMIC AGENT

机译:评价抗心律失常药物作用的系统和方法

摘要

A system and method for evaluating effects of an antiarrhythmic agent. The system includes: an action potential measurement unit for measuring a cardiac action potential of a patient; an ion channel characteristics determination unit for determining ion channel characteristics of the patient using the cardiac action potential; and an antiarrhythmic agent effect evaluation unit for simulating a treatment effect of an antiarrhythmic agent by reflecting characteristics of the antiarrhythmic agent on the determined ion channel characteristics of the patient. The system can conveniently determine the patient's ion channel characteristics by measuring the cardiac action potential of the patient, thereby preventing the risk of gathering cardiomyocytes of the patient. In addition, the system can simulate a treatment effect of an antiarrhythmic agent that usually exhibits a different effect and a different level of safety depending on an individual's ion channel characteristics, without being directly applied to the patient.
机译:一种评估抗心律不齐药物作用的系统和方法。该系统包括:动作电位测量单元,用于测量患者的心脏动作电位;以及离子通道特性确定单元,用于利用心脏动作电位来确定患者的离子通道特性;抗心律失常药效果评价单元,通过将抗心律失常药的特性反映在所确定的患者的离子通道特性上来模拟抗心律失常药的治疗效果。该系统可以通过测量患者的心脏动作电位来方便地确定患者的离子通道特性,从而避免了收集患者心肌细胞的风险。另外,该系统可以模拟抗心律不齐药物的治疗效果,该抗心律不齐药物通常取决于个人的离子通道特性而表现出不同的效果和不同的安全性,而无需直接应用于患者。

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