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BISPECIFIC ANTIBODY-MEDIATED CANCER THERAPY WITH CYTOKINE-INDUCED KILLER CELL
BISPECIFIC ANTIBODY-MEDIATED CANCER THERAPY WITH CYTOKINE-INDUCED KILLER CELL
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机译:细胞因子诱导的杀伤细胞对双特异性抗体介导的癌症治疗
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摘要
Provided are compositions comprising a MSBODY and a cytotoxic immune cell (e.g., Cytokine-induced killer cell) to form Armed Activated CIK cells (ACCs), wherein the MSBODY comprising a first antigen binding moiety that has specificity for a tumor antigen, and a second antigen binding moiety that binds to the cell. Provided are also methods preparing a composition comprising a MSBODY and a cytotoxic immune cell, and methods for treating patients with CIK cells armed with bispecific antibodies.
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