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Serologic test for the rapid diagnosis of active tuberculosis

机译：血清学检查可快速诊断活动性结核

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摘要

The present invention relates to methods and kits for detecting active tuberculosis infection in a subject using serological techniques and a first agent capable of binding an IgG, IgA and/or IgM directed to the first protein present in or on a Mycobacterium tuberculosis membrane vesicle or a Bacillus Calmette-Guerin (BCG) membrane vesicle. Also provided are methods of treating a subject with an active tuberculosis disease.

机译：本发明涉及使用血清学技术和能够结合IgG，IgA和/或IgM的第一试剂在受试者中检测活动性结核感染的方法和试剂盒，所述IgG，IgA和/或IgM针对存在于结核分枝杆菌中或之上的第一蛋白。 / I>膜囊泡或芽孢杆菌 Calmette-Guerin（BCG）膜囊泡。还提供了治疗患有活动性结核病的受试者的方法。 展开▼

著录项

公开/公告号US9841424B2

专利类型

公开/公告日2017-12-12

原文格式PDF

申请/专利权人 ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY;
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申请/专利号US201314434415

发明设计人 JACQUELINE MICHELE ACHKAR;ARTURO CASADEVALL;RAFAEL PRADOS-ROSALES;ANKE ZIEGENBALG;
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申请日2013-10-10

分类号G01N33/569;G01N33/68;

国家 US

入库时间 2022-08-21 12:58:35

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