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COMPOSITIONS AND METHODS FOR DETECTING, TREATING, AND PROTECTING AGAINST FUSOBACTERIUM INFECTION

机译:用于检测,治疗和预防镰刀菌感染的组合物和方法

摘要

The present invention relates to protecting against, treating, and detecting Fusobacteria infections. Compositions and methods derived from nucleic acid and protein sequences of a 40 kDa Adhesin protein are provided to protect against, treat, and detect Fusobacteria infections in a subject. In one aspect, vaccines capable of inducing an immune response to a 40 kDa Adhesin protein are used to protect against Fusobacteria infection. Also, nucleic acid molecules, proteins, immunogens, antibodies, and antisense molecules derived from the sequences of the 40 kDa Adhesin protein may be used to protect against, treat, and detect Fusobacteria infections in a subject.
机译:本发明涉及预防,治疗和检测镰刀菌感染。提供了衍生自40kDa粘附素蛋白的核酸和蛋白序列的组合物和方法,以预防,治疗和检测受试者中的梭菌感染。在一方面,能够诱导对40kDa粘附素蛋白的免疫应答的疫苗被用于预防梭菌感染。而且,源自40kDa粘附素蛋白的序列的核酸分子,蛋白质,免疫原,抗体和反义分子可用于预防,治疗和检测受试者中的梭菌感染。

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