首页> 外国专利> NOVEL ANTIBODY AGAINST RIBOSOMAL PROTEIN S3 AND COMPOSITION FOR DIAGNOSING BIOLOGICAL STRESS

NOVEL ANTIBODY AGAINST RIBOSOMAL PROTEIN S3 AND COMPOSITION FOR DIAGNOSING BIOLOGICAL STRESS

机译:抗核糖体蛋白S3的新型抗体及其用于诊断生物应激的组合物

摘要

The present invention relates to an antibody acting as a stress sensor by sensing various stresses in a living organism including a human. Particularly, the present invention relates to a novel antibody specifically recognizing the above protein modifications, and a composition for diagnosing a biological stress including the antibody, based on the fact that one molecular ubiquitin protein binds to lysine residue of ribosomal protein S3 (rpS3) in a stressed state so that the ubiquitin protein is modified. In addition, the present invention relates to a simple and accurate kit for diagnosing the biological stress using the same.
机译:本发明涉及通过感测包括人在内的活生物体中的各种压力而用作压力传感器的抗体。特别地,本发明涉及一种特异性识别上述蛋白修饰的新型抗体,以及基于一种分子泛素蛋白结合于核糖体蛋白S3(rpS3)的赖氨酸残基这一事实来诊断包括该抗体的生物应激的组合物。应激状态,使泛素蛋白被修饰。另外,本发明涉及一种用于使用其诊断生物压力的简单而准确的试剂盒。

著录项

  • 公开/公告号US2018244761A1

    专利类型

  • 公开/公告日2018-08-30

    原文格式PDF

  • 申请/专利权人 JOON KIM;

    申请/专利号US201715666301

  • 发明设计人 YOUJIN JUNG;HAG DONG KIM;JOON KIM;

    申请日2017-08-01

  • 分类号C07K16/18;C07K14/47;G01N33/68;

  • 国家 US

  • 入库时间 2022-08-21 12:57:45

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