首页> 外国专利> HNF4G-RSPO2 FUSION GENE AND USE THEREOF IN TREATMENT OF CANCER

HNF4G-RSPO2 FUSION GENE AND USE THEREOF IN TREATMENT OF CANCER

机译:HNF4G-RSPO2融合基因及其在癌症治疗中的应用

摘要

The present disclosure provides methods of detecting a fusion gene of HNF4G and RSPO2 in a nucleic acid-containing sample, and a primer set, a probe set and a kit for detecting the fusion gene are also provided. Animal models for a human disease positive for the fusion gene are also provided herein. In addition, the present disclosure relates to the methods for assessing and identifying an agent effective on the fusion gene of HNF4G and RSPO2 or a human disease positive for a fusion gene of HNF4G and RSPO2 and thereby treating said disease are also provided.
机译:本公开提供了在含核酸的样品中检测HNF4G和RSPO2的融合基因的方法,并且还提供了用于检测融合基因的引物组,探针组和试剂盒。本文还提供了对融合基因呈阳性的人类疾病的动物模型。另外,本公开涉及评估和鉴定对HNF4G和RSPO2的融合基因或对HNF4G和RSPO2的融合基因呈阳性的人类疾病有效的药剂并由此治疗所述疾病的方法。

著录项

  • 公开/公告号US2018282814A1

    专利类型

  • 公开/公告日2018-10-04

    原文格式PDF

  • 申请/专利权人 CROWN BIOSCIENCE INC. (TAICANG);

    申请/专利号US201515301381

  • 发明设计人 JIE CAI;HENRY LI;

    申请日2015-04-03

  • 分类号C12Q1/6886;

  • 国家 US

  • 入库时间 2022-08-21 12:57:21

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