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Method and apparatus for a spectral detector for noninvasive detection and monitoring of a variety of biomarkers and other blood constituents in the conjunctiva
Method and apparatus for a spectral detector for noninvasive detection and monitoring of a variety of biomarkers and other blood constituents in the conjunctiva
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机译:用于频谱检测器的方法和设备,用于非侵入性检测和监测结膜中的各种生物标志物和其他血液成分
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摘要
A specialized spectrometer comprises a light source to generate a monochromatic light beam to generate resonance Raman peaks or resonance near infrared absorption peaks from a region of the subject and a reference light source to illuminate the region with a reference light beam. The light energy from the resonance Raman peaks can be measured with a detector coupled to an optical wavelength separator. A portion of the reference beam scattered from the region can be measured with a reference detector. An amount of the constituent can be determined with a processor in response to the resonance Raman peaks measured with the detector and the portion of the reference beam measured with the reference detector. The illumination of the region with reference beam with the monochromatic beam allows accurate determination of the amount of the constituent, and the amount may comprise a concentration, such as an amount per unit volume.
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