首页>
外国专利>
Depth-resolved spatial-domain low-coherence quantitative phase microscopy for unstained tissue and cells
Depth-resolved spatial-domain low-coherence quantitative phase microscopy for unstained tissue and cells
展开▼
机译:深度分辨的空间域低相干定量相显微镜,用于未染色的组织和细胞
展开▼
页面导航
摘要
著录项
相似文献
摘要
Provided are systems, methods, and other embodiments associated with depth-resolved spatial-domain low-coherence quantitative phase microscopy for high-throughput analysis of 3D nanoscale architectural alterations in unstained tissue and cells. A spatial-domain low-coherence quantitative phase microscopy apparatus includes a drOPD mapping module, a transmission phase imaging module, and a bright-field and transmission phase imaging module. The drOPD mapping module includes a reflection-mode low-coherence spectral interferometry for drOPD mapping of unstained tissue. The transmission phase imaging module includes transmission quantitative phase imaging of unstained and stained tissue and produce an image registration reference. The bright-field and transmission phase imaging module includes bright-field imaging of H&E-stained tissue for nuclei identification and pathology correlation.
展开▼