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Method And System For Adaptive Scheduling Of Clinical Assessments

机译:临床评估自适应调度的方法和系统

摘要

Methods and systems providing adaptive assessment of a physical subject to efficiently collect assessment data and modify an assessment schedule based on the analyses. The methods and systems can control the timing of each assessment in order to collect data at times and under conditions that are most informative about the physical subject. Such adaptive methods and systems significantly minimize the frequency of data collection without loss in accuracy or precision and can increase test reliability through reduction in redundancy. The ability to estimate an unknown, underlying function using a small number of free parameters that remain constant regardless of the number of data points being estimated substantially reduces the error of the function estimate. Because estimates of the measurement error are achieved with a minimum of sampled assessments, and with great accuracy, the statistical power of clinical trials, for example, can be greatly increased.
机译:提供对物理对象的自适应评估以有效地收集评估数据并基于该分析修改评估时间表的方法和系统。所述方法和系统可以控制每次评估的时间,以便在最及时地了解物理受试者的时间和条件下收集数据。这样的自适应方法和系统可显着最小化数据收集的频率,而不会降低准确性或精度,并可通过减少冗余来提高测试的可靠性。使用少量恒定的自由参数来估计未知的基础函数的能力,无论所估计的数据点的数量如何,这些参数都保持不变,从而大大降低了函数估计的误差。由于可以通过最少的采样评估并且以很高的准确性来实现对测量误差的估计,因此可以大大提高例如临床试验的统计能力。

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