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Engineering individually addressable cellular spheroids using aqueous two-phase systems
Engineering individually addressable cellular spheroids using aqueous two-phase systems
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机译:使用水性两相系统工程化可单独寻址的细胞球体
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摘要
Provided are multi-phase systems that may be used to prepare a three-dimension aggregate of cells referred to as a cellular spheroid. The multi-phase system includes a droplet of an aqueous polymer phase within an immersion aqueous polymer phase. The droplet of the droplet aqueous polymer phase contains a three-dimensional aggregate of cells (cellular spheroid). Types of cells that may be used in the multi-phases system include stem cells and cancer cells. The cellular spheroids with the multi-phase system may be used to monitor cell growth in three-dimensional systems, or screen drugs in a three-dimension aggregate of cells.
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