首页>
外国专利>
Method for screening substance capable of inhibiting abnormal splicing causative of onset or progress of disease
Method for screening substance capable of inhibiting abnormal splicing causative of onset or progress of disease
展开▼
机译:能够抑制引起疾病发作或进展的异常剪接的物质的筛选方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A compound and a pharmaceutical composition for disease associated with an abnormal splice variant, use of the compound and the pharmaceutical composition, or a screening method of the compound and the pharmaceutical composition are provided. One or more embodiments disclose a compound expressed by the following formula (I) or (I′) or prodrugs or pharmaceutically acceptable salts thereof. Another one or more embodiments disclose a screening method using a DNA construct that is fused, arranged, or constructed so as to express different reporter genes for a wild-type splice variant and an abnormal splice variant that contributes to the development or progression of disease;; 展开▼