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FGF-2 variants having N-terminal deletions and increased receptor selectivity and methods of use thereof
FGF-2 variants having N-terminal deletions and increased receptor selectivity and methods of use thereof
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机译:具有N端缺失和增加的受体选择性的FGF-2变体及其使用方法
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摘要
The present invention relates to the design, manufacture and use of fibroblast growth factor (FGF) polypeptides having improved receptor specificity. In particular, the invention relates to isolated FGF2 polypeptides comprising a truncated N-terminus and optionally N-terminal amino acid substitutions. The present invention provides polypeptides, nucleic acids encoding the polypeptides, compositions comprising same and methods for use thereof.
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