Corticosteroid formulations to keep concentrations of corticosteroid in synovial Liquid

摘要

Compositions and Methods for Achieving and maintaining maximum Analgesic effect after intra-articular Administration of corticosteroid formulations.Extended release formulations, for example, corticosteroid formulations of sustained controlled release or extended release formulations, which include, for example,Controlled or sustained release formulations of Triamcinolone Acetonida (TCA, for its acronym in English), Fluticasone propionate, cortisol, ciclesonide (monopropionato)Beclomethasone Dipropionate, dexamethasone, beclomethasone, budesonide, desisobutiril - ciclesonide and / or Mometasone furoateProducing a maximum Analgesic effect than the acute Analgesic effect provided by Standard corticosteroid suspensions.Including suspensions of corticosteroid Release not extended and that are also associated with a clinically insignificant effect on the production of endogenous cortisol after theIntra articular Administration, epidural, Intrathecal, intrabursal or another type of Local Administration.