COMPLEX OF IMMUNOGENIC POLYPROTEINS OF M. hyopneumoniae, SYNTHETIC GENE OF THE COMPLEX OF IMMUNOGENIC POLYPROTEINS OF M. hyopneumoniae, ANTIGENIC COMPOSITION, PROCESS OF OBTAINING A COMPLEX OF IMMUNOGENIC POLYPROTEINS OF M. hyopneumoniae

摘要

The complex of polyprotein imunogu00eanicas of M. hyopneumoniae, synthetic gene coding of complex imunogu00eanicas polyproteins of M.Hyopneumoniae, antigenic composition, process for obtaining a complex depoliprotenas imunogu00eanicas M.Hyopneumoniae, use of a composition based on complex imunogu00eanicas polyproteins of M.Has the present invention refers to a complex of polyproteins containing regions of antigens derived imunogu00eanicas p36, P46, HSP, nrdf, p97, mhp271 and P216 M.Hyopneumoniae, regions are merged with the segments of the carrier proteins rrp4, rrp41 and rrp42 of P. abyssi, forming a complex one.The present invention provides additional other objects: (I) a gene coding the polyprotein complex, said complex being based on exossomo of P.Abyssi that door copies of vaccine antigens of M.Hyopneumoniae; (II) an antigenic composition comprising the complex of polyproteins of the invention.Optionally one or more adjuvants and / or additives and a pharmacologically acceptable vehicle; (lil) a process of obtaining the said poliproteu00edna complex; and (IV) uses of said complex and said withThe position in the treatment and prevention of infections caused by M. hyopneumoniae.